abstract：BACKGROUND AND AIMS:Insulin-like growth factors (IGFs) are closely related to hepatocellular carcinoma growth. The study aim was to investigate the effects of IGF-IR and IGF-IIR antisense gene transfection on the biological behaviors of SMMC-7721 human hepatoma cells. METHODS:7721-IGF-IR-AS cells (human hepatoma SMMC-...

journal_title：Journal of gastroenterology and hepatology

authors： Yang JM,Chen WS,Liu ZP,Luo YH,Liu WW

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic ultrasonography (EUS) is a useful tool for the evaluation of gastric wall infiltration including gastric lymphoma. The aims of this study were to characterize gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphoma according to EUS findings and to evaluate the role of a miniat...

journal_title：Journal of gastroenterology and hepatology

authors： Yeh HZ,Chen GH,Chang WD,Poon SK,Yang SS,Lien HC,Chang CS,Chou G

更新日期：2003-02-01 00:00:00

abstract：AIM:To evaluate the characterization of liver hemangiomas and malignant tumors using power Doppler sonography before and after intravenous injection of a sonocontrast agent. METHODS:Forty-five patients with 57 liver tumors (22 hemangiomas, 24 metastases, 10 hepatocellular carcinomas (HCC) and one cholangiocellular car...

journal_title：Journal of gastroenterology and hepatology

authors： Karabacakoglu A,Karakose S,Cil AS,Kaya A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIM:The stool antigen test, the HpSA test, has been validated mainly in Western countries, but not properly in the Chinese population. Recently, another stool antigen test, the Apollo test, was developed, but its accuracy has rarely been validated. The aim of this study is to compare the accuracy of thes...

journal_title：Journal of gastroenterology and hepatology

authors： Wong BC,Xia HH,Cheung HK,Ng FH,Wong SY,Chow KC,Lin SK,Yin Y,Wong WM,Yuen MF,Lam SK

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:All gut movements are claimed to be activated essentially by the concentric contraction of the circular muscle, moving the chyme aborally. The role of the longitudinal smooth muscle of the small intestine in gut motility is poorly understood; this point was investigated in the current study. METHODS:The abd...

journal_title：Journal of gastroenterology and hepatology

authors： Shafik A,Shafik AA,Ahmed I

更新日期：2002-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a member of the virus family Flaviviridae. At present HCV is classified into a discrete hepacivirus genus and is represented by six clades according to genome sequencing. Each clade is further divisible into subtypes, which may prove important for the study of clinical differences and epidem...

journal_title：Journal of gastroenterology and hepatology

authors： Howard CR

更新日期：2002-12-01 00:00:00

abstract：:Worldwide the need for effective therapy for chronic hepatitis B is similar to that for chronic hepatitis C. Current licensed treatment for chronic hepatitis B (interferon (IFN)-alpha, lamivudine) does not significantly alter the natural history of the disease because the frequency of sustained response is too low; ho...

journal_title：Journal of gastroenterology and hepatology

authors： Schalm SW,De Man RA,Janssen HL

更新日期：2002-12-01 00:00:00

abstract：:Extracorporeal liver assist devices have been used for more than five decades to support patients with liver failure. Numerous modifications have been made to both biological as well as mechanical liver assist devices. Possibly, an ideal liver assist device would be one that would perform optimal detoxification and sy...

journal_title：Journal of gastroenterology and hepatology

authors： Kapoor D

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:A daily injection of glycyrrhizin (Stronger Neo-Minophagen C (SNMC) containing 40 mg glycyrrhizin in a 20 mL ampoule) lowers alanine aminotransferase (ALT) levels in patients with chronic viral hepatitis. METHODS:The therapeutic effects of intermittent administration of SNMC three times a week for 12 weeks ...

journal_title：Journal of gastroenterology and hepatology

authors： Miyake K,Tango T,Ota Y,Mitamura K,Yoshiba M,Kako M,Hayashi S,Ikeda Y,Hayashida N,Iwabuchi S,Sato Y,Tomi T,Funaki N,Hashimoto N,Umeda T,Miyazaki J,Tanaka K,Endo Y,Suzuki H

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:In order to evaluate some possible risk factors for the spread of hepatitis C infection a case-control study was undertaken. METHODS:The study population consisted of first time blood donors referred to the Iranian Blood Transfusion Organization. Enzyme-linked immunosorbent assay and recombinant immunoblot ...

journal_title：Journal of gastroenterology and hepatology

authors： Alavian SM,Gholami B,Masarrat S

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND AIM:It has been suggested that Chlamydia is an organism that may have the potential to cause inflammatory bowel disease (IBD) in susceptible individuals. Chlamydia pneumoniae has emerged as an important human pathogen in the last decade. The objective of the present study was to investigate the frequency...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Li D,Wilson I,Chadwick VS

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Microbial agents are a possible cause of ulcerative colitis. We have previously reported evidence of bacteria invading the colonic mucosa of patients with ulcerative colitis. We have isolated bacteria from inflamed colonic mucosa, examined the localization of the species in the mucosa, and assayed for serum ...

journal_title：Journal of gastroenterology and hepatology

authors： Ohkusa T,Sato N,Ogihara T,Morita K,Ogawa M,Okayasu I

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Although there is strong implication that retinoids regulate Ito cell proliferation and collagen synthesis, results from in vivo studies on the relationship between vitamin A and liver fibrosis are conflicting. The present study focuses on the role of vitamin A in carbon tetrachloride (CCl4)-induced fibrosis...

journal_title：Journal of gastroenterology and hepatology

authors： Vollmar B,Heckmann C,Richter S,Menger MD

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:There is a wide variation in the prevalence of peptic ulcer in India both before and since the use of endoscopy. We studied the prevalence of peptic ulcer disease in a community in northern India and its relationship with Helicobacter pylori infection. METHODS:A house-to-house survey of residents aged 15 ye...

journal_title：Journal of gastroenterology and hepatology

authors： Singh V,Trikha B,Nain CK,Singh K,Vaiphei K

更新日期：2002-06-01 00:00:00

abstract：:AL amyloidosis complicating multiple myeloma is rare but well recognized. Endoscopic appearances of amyloid in the gastrointestinal tract can, however, be highly variable. Macroscopic appearances of the duodenum can range from scalloping (often seen in celiac disease) to that of duodenitis; erosive disease, frank ulce...

journal_title：Journal of gastroenterology and hepatology

authors： Hurlstone DP

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:: Previously, we have observed that highly unsaturated dietary (n-3) fatty acids inhibit cell proliferation in conjunction with stimulation of insulin-like growth factor-binding protein (IGFBP)-6 secretion in Caco-2 cells, a human colon carcinoma cell line. METHODS:: To test the converse hypothesis that inh...

journal_title：Journal of gastroenterology and hepatology

authors： Kim EJ,Schaffer BS,Kang YH,Macdonald RG,Park JH

更新日期：2002-05-01 00:00:00

abstract：:The approach of a pediatric hepatologist in managing children with hepatitis C virus (HCV) differs from adult practice, because the pediatric hepatologist is dealing with the beginning of a chronic illness in which long-term outcomes will not occur for 20 or 40 years, and it is not possible to predict in the early sta...

journal_title：Journal of gastroenterology and hepatology

authors： Hardikar W

更新日期：2002-04-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Australia receives many migrants from countries with a high prevalence of hepatitis C infection. General practitioners, who are often the first health professionals consulted, need to be aware of risk factors and complications associated with hepatitis C in this group. METHODS:Four hundred and forty-seven g...

journal_title：Journal of gastroenterology and hepatology

authors： Dev A,Sievert W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:To elucidate the incidence of the rare cases of icteric type hepatocellular carcinoma (IHCC), we conducted a retrospective study. The clinical outcomes of IHCC cases were also analyzed. METHODS:From January 1986 to December 1997, newly diagnosed HCC cases were evaluated and reviewed from an admission regist...

journal_title：Journal of gastroenterology and hepatology

authors： Huang JF,Wang LY,Lin ZY,Chen SC,Hsieh MY,Chuang WL,Yu MY,Lu SN,Wang JH,Yeung KW,Chang WY

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：:The hepatitis C virus was first identified in 1989. It causes chronic hepatitis, cirrhosis and hepatocellular carcinoma. Global anti-HCV prevalence is 1-3%. Contaminated blood product, dirty needles and instruments, and injection drug use are the main parenteral routes of transmission. Cultural practices, such as acup...

journal_title：Journal of gastroenterology and hepatology

authors： Leung NW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Accumulation of endogenous opioids and overproduction of nitric oxide has been reported in cholestatic mice. It is well known that endogenous opioids and nitric oxide alter the susceptibility of experimental animals to different models of seizure. METHODS:The alterations in clonic seizure thresholds, induce...

journal_title：Journal of gastroenterology and hepatology

authors： Homayoun H,Sayyah M,Dehpour AR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:It has been proposed that the expression of Fas ligand (Fas L) in tumors may play an important role in immune escape. This study was undertaken to test a 'counterattack' theory as a mechanism of immune escape in gastric carcinoma. METHODS:Expression of Fas and Fas L was examined in the human gastri...

journal_title：Journal of gastroenterology and hepatology

authors： Lee TB,Min YD,Lim SC,Kim KJ,Jeon HJ,Choi SM,Choi CH

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:A few cases are reported of liver neoplasms observed in patients with glycogen storage disease type 1a (GSD1a). Genetic analysis was carried out in adult Japanese patients with GSD1a and their family members, and hepatic tumors were also investigated in these patients. METHODS:DNA was extracted fro...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura T,Ozawa T,Kawasaki T,Nakamura H,Sugimura H

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:To evaluate the accuracy of two rapid whole blood tests (the BM-Test Helicobacter pylori and the QuikPac IV One Step H. pylori Whole Blood Test), and compare this to a conventional quantitative ELISA test (HEL-p TEST II). METHODS:Helicobacter pylori status in dyspeptic patients was assessed by culture, hist...

journal_title：Journal of gastroenterology and hepatology

authors： Chen TS,Chang FY,Lee SD

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND AIM:Autoimmune hepatitis (AIH) is a chronic disease of unknown etiology, which usually progresses to cirrhosis if not diagnosed and treated promptly. Data on long-term follow up in children with AIH are scant. The aim of this study is to assess the long-term outcome of autoimmune hepatitis in children wi...

journal_title：Journal of gastroenterology and hepatology

authors： Saadah OI,Smith AL,Hardikar W

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND AIM:T-cell activation, mediated by the interaction with major histocompatibility complex (MHC)-peptide complexes and B7 costimulatory molecules on antigen-presenting cells, is an essential event in the pathogenesis of inflammatory bowel disease (IBD). We investigated the expression of B7 costimulatory mo...

journal_title：Journal of gastroenterology and hepatology

authors： Grose RH,Howarth GS,Xian CJ,Hohmann AW

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:By analyzing a tumor growth of hepatocellular carcinoma (HCC) detected in sustained responders (SR) to interferon (IFN) therapy for chronic hepatitis C, we sought to determine the duration of follow up in SR that would be sufficient to detect HCC. In addition, we sought to elucidate the presence of HCC, whic...

journal_title：Journal of gastroenterology and hepatology

authors： Toyoda H,Kumada T,Honda T,Hayashi K,Katano Y,Nakano I,Hayakawa T,Fukuda Y

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Hyposplenism has been described in patients with alcoholic cirrhosis (AC). However, no data are available regarding hyposplenism in patients with non-alcoholic cirrhosis (NAC) and other forms of portal hypertension such as extrahepatic portal venous obstruction (EHPVO). The aim is to study the splen...

journal_title：Journal of gastroenterology and hepatology

authors： Satapathy SK,Narayan S,Varma N,Dhiman RK,Varma S,Chawla Y

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIM:The PyloriTek Test Kit (a 1-h rapid urease test) was developed for the rapid diagnosis of Helicobacter pylori (H. pylori) during endoscopy. Most studies were performed in Western populations. The aim of this study was to evaluate the PyloriTek test for the diagnosis of H. pylori infection in Chinese ...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Wong BC,Tang VS,Lai KC,Yuen ST,Leung SY,Hu WH,Lam SK

更新日期：2001-09-01 00:00:00

abstract：AIM:The clinical presentation of four children and adolescents (two males and two females with a mean age of 12.4 years; range 9-16 years) with colorectal spirochetosis is discussed. RESULTS:Symptoms included persistent diarrhea (n = 2), rectal bleeding (n = 1) and abdominal pain (n = 2). In all patients, colorectal s...

journal_title：Journal of gastroenterology and hepatology

authors： Heine RG,Ward PB,Mikosza AS,Bennett-Wood V,Robins-Browne RM,Hampson DJ

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND AIM:Tumor thrombi in the bile duct caused by hepatocellular carcinoma (HCC), and cholangiocarcinoma show polypoid lesions on cholangiographic findings. This study prospectively compared the images of intraductal ultrasonography between HCC and polypoid cholangiocarcinoma. METHODS:In five patients with t...

journal_title：Journal of gastroenterology and hepatology

authors： Tamada K,Isoda N,Wada S,Tomiyama T,Ohashi A,Satoh Y,Ido K,Sugano K

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to clinicopathologically distinguish the pathogenesis of gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma without a MALT lymphoma component (DLL). METHODS:We investigated clinicopathological features of these gastric lymphomas inc...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Haruma K,Kitadai Y,Masuda H,Miyamoto M,Ito M,Kamada T,Tanaka S,Uemura N,Yoshihara M,Sumii K,Shimamoto F,Chayama K

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Several etiologic factors including hepatitis viruses, alcohol and aflatoxin have been implicated in the pathogenesis of hepatocellular carcinoma (HCC). There is, however, limited information from the Indian subcontinent. METHODS:Seventy-four consecutive cases of HCC were studied. A detailed history, tests ...

journal_title：Journal of gastroenterology and hepatology

authors： Sarin SK,Thakur V,Guptan RC,Saigal S,Malhotra V,Thyagarajan SP,Das BC

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Hepatic steatosis has been shown to be associated with lipid peroxidation and hepatic fibrosis in a variety of liver diseases including non-alcoholic fatty liver disease. However, the lobular distribution of lipid peroxidation associated with hepatic steatosis, and the influence of hepatic iron stor...

journal_title：Journal of gastroenterology and hepatology

authors： MacDonald GA,Bridle KR,Ward PJ,Walker NI,Houglum K,George DK,Smith JL,Powell LW,Crawford DH,Ramm GA

更新日期：2001-06-01 00:00:00

abstract：:Hepatitis C virus infection is a global health problem; however, the interaction between pregnancy and chronic hepatitis C remains controversial. A Taiwanese woman with chronic hepatitis C had an uncomplicated pregnancy and gave birth to a female baby through spontaneous vaginal delivery. The serum levels of alanine a...

journal_title：Journal of gastroenterology and hepatology

authors： Chen JD,Chung JL,Kao JH,Chen DS

更新日期：2001-06-01 00:00:00

abstract：:Gastric cancer usually shows poor sensitivity to chemotherapy, and the presence of lymph node metastases is associated with extremely poor prognosis, especially when the number of such nodes is more than 10. We report here a case of advanced gastric cancer with histopathologically confirmed metastases in 15 regional l...

journal_title：Journal of gastroenterology and hepatology

authors： Shigemitsu K,Naomoto Y,Matsuno T,Gochi A,Isozaki H,Tanaka N

更新日期：2001-05-01 00:00:00

abstract：AIMS:The aim of this study was to determine the cumulative rate of flare-up of serum alanine aminotransferase (ALT) level during a 10-year follow-up period, and characterize the clinical, virologic features in 120 hepatitis C virus (HCV) RNA-positive asymptomatic carriers with persistently normal ALT levels for 6 month...

journal_title：Journal of gastroenterology and hepatology

authors： Tsuji K,Yamasaki K,Yamanishi M,Kawakami M,Shirahama S

更新日期：2001-05-01 00:00:00

abstract：:Herein, we report on an adult with intussusception of an invaginated Meckel's diverticulum presenting mainly with acute intermittent lower gastrointestinal bleeding, whereas the common symptom of abdominal pain, indicating intussusception, was absent. Colonoscopy revealed a reducible polypoid lesion in the ileocecal a...

journal_title：Journal of gastroenterology and hepatology

authors： Lu CL,Chen CY,Chiu ST,Chang FY,Lee SD

更新日期：2001-04-01 00:00:00